Times when it is good that I work with mostly men: when I go to a conference and I get my own hotel room (yay, I don't have to clean!!).
Times when it is not good that I work with mostly men: when I stay out of work one day due to wicked bad cramps. I come back the next day to a lot of "feeling better?" "What was wrong?". Not that I have a problem saying "oh, my cramps were killing me!". But I don't want to make anyone uncomfortable. So, I just say, "Oh, you know, just generally feeling bad".